A new 65-seat theatre in Fulham will open next month above a refurbished bar and brasserie, the Eel Brook, at 65 New King's Road.
Named the London Theatre Workshop, the first season has a strong musical theatre focus.
Artistic director Ray Rackham said: "I am thrilled we have convinced Greene King, the landlord of this beautiful building, that London Theatre Workshop could really make something of the space... It is my intention to ensure that the London Theatre Workshop truly becomes a destination venue for all."
The inaugural production, running from 10 to 29 March, is a revival of Adam Gwon's chamber musical Ordinary Days, centring on four young New Yorkers.
The cast includes Oliver Watton ( Hollyoaks, Fiyero in Wicked), Marcia Brown (Assassins, Pleasance), Anton Tweedale and Olga-Marie Pratt.
The first season will also see a revival of Eugene O'Neill's Ah, Wilderness, the UK professional premiere of Harvey Fierstein and John Bucchino's Broadway musical A Catered Affair', a "new celebration" of Stephen Sondheim's love songs, Just Another Love Story'', and a new show centring on Judy Garland.
As an opening offer, tickets for all first three productions, Ordinary Days, Ah Wilderness and A Catered Affair, are available at the combined price of £30.
For more information visit londontheatreworkshop.co.uk