Jamie-Lee is best known for her breakout performance as Michelle Mallon in the award-winning Derry Girls, and as Rose Gill in Series 1 & 2 of Screw. She is currently filming the lead role in a new BBC comedy series, Hopley Hall. She will next be seen in Girl Group, written by and starring Rebel Wilson, and Skintown, (Screen NI, Keeper Pictures & Cyprus Avenue Films), which recently won the Sean Connery Prize for Feature Film Making Excellence at the 2026 Edinburgh International Film Festival. Television credits include: Derry Girls, Screw (Channel 4); Leonard and Hungry Paul, Faithless (BBC) and The Feud (Channel 5). Film credits include: Unwelcome (Warner Bros/Tempo Productions) and Redeeming Love (Mission Pictures International). Jamie-Lee authored, associate produced and starred in the Channel 4 documentary Jamie-Lee O’Donnell: The Real Derry, for which she won the RTS NI Award for Best On-Screen Talent
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