Titchmarsh, best known for his work as a TV presenter, said: "I am thrilled and delighted to be joining this tremendous production which celebrates my all-time favourite children's book."
The production, directed and choreographed by Will Tuckett, makes its return to the West End after an Olivier Award-winning run last Christmas. It will be at the Vaudeville Theatre from 26 November 2014 to 17 January 2015.
Based on Kenneth Grahame's timeless classic, the adventures of four woodland friends are retold through dance, song, music and puppetry. From a dusty old attic a wonderful tale unfolds; the peaceful riverbank world is rocked by a speeding car, a racing train and criminal deeds cooked up in the Wild Wood.
Titchmarsh, who replaces Tony Robinson as the narrator, has enjoyed a long career in television, presenting Gardener's World and Ground Force as well as his own show on ITV. He has written over 50 books as well as nine novels.
Further casting for Wind in the Willows will be announced soon.