As previously tipped by Whatsonstage.com, Jamie Lloyd's second production in his five-play residency at the Trafalgar Studios will be Harold Pinter's The Hothouse, which runs from 9 May to 3 August (previews from 9 May).

The production will star stage veteran Simon Russell Beale as Roote and John Simm as Gibbs, and will run after Lloyd's Macbeth, starring James McAvoy, which finishes on 27 April.

First performed at the Hampstead Theatre in 1980, The Hothouse is set on Christmas Day in a nameless state-run mental institution where the inmates are subjected to a tirade of mindless cruelty. A maniacal and self-obsessed leader breeds a contagion of hierarchical savagery amongst his staff, who thrive on a noxious diet of delusion and deceit.

Simon Russell Beale's numerous stage credits include, most recently, Privates on Parade (Noel Coward Theatre), Collaborators, Timon of Athens, London Assurance (National Theatre) and Deathtrap (Noel Coward). He has won numerous awards for his stage work, including two Olivier awards. Film credits include The Deep Blue Sea and My Week With Marilyn, and recent TV credits include Henry IV I and II, A Dance to the Music of Time and Spooks.

John Simm's stage credits include Elling (Bush/Trafalgar Studios), Speaking in Tongues (Duke of York's), Hamlet and Betrayal (Sheffield Theatres). He is also well known for his TV credits, which include Life on Mars, Doctor Who, Exile, Mad Dogs and The Village.

As part of the Trafalgar Transformed season, all tickets will be £15 on Mondays. The Hothouse is the second is Jamie Lloyd's residency, and will have designs by Soutra Gilmour. It runs at the Trafalgar Studios until 3 August.

Lloyd said: "It is a dream come true to be working with Simon Russell Beale and John Simm on this funny, peculiar and frightening play as a part of Trafalgar Transformed. The Hothouse is the third Pinter project I have worked on (following The Caretaker and The Lover & The Collection) and I am thrilled to be introducing Harold's work to a young, diverse audience via our £15 Mondays ticket scheme."