AO Arena (formerly Manchester Arena)

One Night Only: 01 October 2021

Deep Purple

One Night Only: 02 October 2021

The Weeknd

One Night Only: 24 October 2021

Bon Iver

One Night Only: 27 October 2021

Professor Brian Cox - Horizons

One Night Only: 29 October 2021

Disney on Ice - Find Your Hero

Performances begin: 03 November 2021

Blondie - Against The Odds

One Night Only: 09 November 2021

Steps - What the Future Holds

Performances begin: 11 November 2021

Sir Elton John - Farewell Yellow Brick Road

One Night Only: 19 November 2021

AJ Tracey

One Night Only: 20 November 2021

JLS - Beat Again

Performances begin: 23 November 2021

Pete Tong - Pete Tong presents Ibiza Classics

One Night Only: 27 November 2021

Sir Elton John - Farewell Yellow Brick Road

One Night Only: 01 December 2021

James - + The Happy Mondays

One Night Only: 03 December 2021

D-Block Europe

One Night Only: 05 December 2021

Tom Jones - A Celebration

One Night Only: 06 December 2021

Gary Barlow - Music Played By Humans - The Tour

One Night Only: 09 December 2021

Madness - The Ladykillers Tour

One Night Only: 11 December 2021

Michael Ball and Alfie Boe - Together at Christmas

One Night Only: 16 December 2021

Shagged, Married, Annoyed

One Night Only: 19 December 2021

Bill Bailey - En Route to Normal

One Night Only: 22 December 2021

L.O.L. Surprise! Live

Performances begin: 30 December 2021

Strictly Come Dancing - The Live Tour

Dance/Ballet

Performances begin: 29 January 2022

James Blunt - The Stars Beneath My Feet

One Night Only: 04 February 2022

Simply Red

One Night Only: 06 February 2022

Dave

One Night Only: 24 February 2022

John Bishop - Right Here, Right Now

Performances begin: 25 February 2022

The Lumineers

One Night Only: 02 March 2022

Snoop Dogg - I Wanna Thank Me

One Night Only: 05 March 2022

Ozzy Osbourne - No More Tours 2

One Night Only: 09 March 2022

The Wanted

One Night Only: 13 March 2022

Stereophonics

One Night Only: 18 March 2022

Hans Zimmer

One Night Only: 24 March 2022

Planet Earth II in Concert

One Night Only: 25 March 2022

Jeff Wayne's Musical Version of The War of The Worlds

Musical

One Night Only: 01 April 2022

Royal Blood

One Night Only: 02 April 2022

Dua Lipa - Future Nostalgia Tour

One Night Only: 15 April 2022

Craig David - Hold That Thought

One Night Only: 23 April 2022

Little Mix - The Confetti Tour

Performances begin: 06 May 2022

Gregory Porter

One Night Only: 08 May 2022

Alan Partridge - STRATAGEM

One Night Only: 12 May 2022

Whitesnake, Foreigner and Europe

One Night Only: 18 May 2022

Pet Shop Boys - Dreamworld

One Night Only: 20 May 2022

The Script - I Want it All

One Night Only: 21 May 2022

Alice Cooper

One Night Only: 27 May 2022

Queen + Adam Lambert

Performances begin: 30 May 2022

Magic Mike Live

Musical

One Night Only: 02 June 2022

Celine Dion - Courage - World Tour

Performances begin: 05 June 2022

Billie Eilish

Performances begin: 07 June 2022

Alicia Keys - ALICIA The World Tour

One Night Only: 11 June 2022

Diana Ross - Top of the World Tour

One Night Only: 14 June 2022

Barry Manilow

One Night Only: 16 June 2022

Kings of Leon

One Night Only: 05 July 2022

Joe Lycett - More, More, More! How Do You Lycett? How Do You Lycett?

One Night Only: 20 September 2022

Jason Manford - Like Me

One Night Only: 15 October 2022

Sir Elton John - Farewell Yellow Brick Road

Performances begin: 31 May 2023