York Theatre Royal has announced casting for its upcoming revival of Harold Pinter's Betrayal, which runs fron 3 to 18 October 2014.
Ryan's screen credits include Shameless and the BAFTA-winning film Elizabeth; Hesketh has just filmed new BBC series The Missing.
Set in the 1960s and 70s, the play - which centres on an extramarital affair viewed backwards over time - is said to be based on Pinter's real life affair with Joan Bakewell.
Casting has been announced for Pocket Dream, a 60-minute version of Propeller's acclaimed production of A Midsummer Night's Dream.
Darrell Brockis, James Tucker, Matthew McPherson and Lewis Hart will all revisit their roles from the 2013/14 tour, joined by Propeller stalwart Finn Hanlon and newcomer Antony Jardine.
The production will be directed by Edward Hall and begins its tour at the EM Forster Theatre in Tonbirdge on 8 September.
Adam Rapp's one-woman play The Edge of our Bodies at the Gate Theatre will star Shannon Tarbet, recently seen in Hotel (National Theatre), Rapture, Blister, Burn (Hampstead Theatre) and Circle Mirror Transformation (Royal Court).
Directed by Christopher Haydon and running from 25 September to 18 October, the play centres on a pregnant teenager who "must learn to untangle the real world outside from the thorns of her imagination".